Genes and oral cancer.

Oral cancers have been one of the leading causes of deaths particularly in the developing countries. Prime reason for this high mortality and morbidity is attributed to the delay in diagnosis and prompt treatment. Relentless research in the field of oncology has led to the advent of novel procedures for the early detection of oral cancers. Molecular biology is highly promising in this regard. It is a procedure that detects alterations at a molecular level much before they are seen under a microscope and much before clinical changes occur. Molecular studies serve as the basis by which we will eventually be able not only to augment clinical assessment and classification of oral lesions but also predict malignant potential of oral lesions, thus reducing the incidence and increasing the scope for early diagnosis and treatment of oral cancers. However, making such sophisticated tools available for the common man in developing countries is one of the most important challenges faced today.

The relationship of platelet phospholipase A, and tumor / 中国癌症杂志

Phospholipase A2(PLA2) is an enzyme family which widely distributed in nature. It is related to many important function in physiology and pathology. Among the enzymes, a small molecule PLA2 (platelet PLA2) is closely related to tumor. The study of platelet PLA2 and tumor is reviewed.